For psoriasis, apply a thin film of Tazarotene to the affected areas each evening. Make sure your skin is dry before you begin. Keep the gel away from normal skin.

To treat acne, first wash your face and dry it thoroughly. Then apply a thin film of Tazarotene to the acne eruptions. Repeat each evening.

More common side effects may include:
Burning, dry skin, irritation, itching, skin pain, skin peeling, skin reddening, stinging, worsening of psoriasis

Certain drugs can increase your sensitivity to sunlight. Check with your doctor before taking any other medication while using Tazarotene, and be especially cautious when using the following:

Major tranquilizers such as Compazine, Stelazine, and Thorazine
Quinolone antibiotics such as Cipro, Floxin, and Noroxin
Sulfa drugs such as Bactrim and Septra
Tetracycline antibiotics such as Achromycin V, Minocin, and Vibramycin
Thiazide-type water pills such as Dyazide and HydroDIURIL

Excessive external use of Tazarotene can cause redness, peeling, and skin discomfort.

If you miss a dose, apply it as soon as you remember. If it is almost time for the next dose, skip the one you missed and go back to your regular schedule.

Tazarotene cream is used to treat psoriasis, acne, and signs and symptoms (appearance and texture) of premature aging of the skin caused by overexposure to the sun (photodamage).

Store at room temperature.

Tazarotene may cause severe birth defects. If you are a woman in your child-bearing years, do not use Tazarotene if there is any chance that you are pregnant. Your doctor should give you a pregnancy test within 2 weeks of starting Tazarotene therapy, and you should take reliable birth control measures as long as you use the drug. If you accidentally become pregnant, stop using Tazarotene and call your doctor immediately.